In its annual report on the biotechnology industry, Ernst & Young warns that the global financial crisis threatens to render the business models that have driven the sector to date unsustainable. The funding drought is placing these business models that fueled biotechnologies growth since its inception under unprecedented strain, the reports says. But emerging trends will likely open the way for new and more sustainable ways of funding drug development, according to E&Y. We spoke to Glen Giovannetti, Ernst & Young’s Global Biotechnology Leader, about the pressures on the industry today, why existing business models may not work going forward and what new business models the changing landscape point to for the future.