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The Burrill Weekly Brief | March 31, 2014

BY THE NUMBERS

 

Biotech sector drags on Wall Street

 

Jittery investors drove a second week of a selloff of biotech stocks as investors took their profits in some of the biggest outperformers worried that the sector had reached a peak. Gilead Sciences fell 4.9 percent and Biogen Idec was off by 7.7 percent for the week. For the week, the Burrill Biotech Select Index fell. That compared to the Nasdaq Composite Index, down 2.8 percent, and the S&P 500, down 0.5 percent. The Dow Jones Industrial Average ended the week flat.

 

Veterinary products company Heska was the week's biggest gainer, up 20.8 percent after it reported fourth quarter results. The company posted a record operating income of $2.8 million, compared to $720,000 in the same period last year.

 

Exelixis' shares were hammered after the biotech said its interim analysis done and the late-stage trial of cabozantinib as a treatment for prostate cancer would continue to as is. For investors, this meant that the investigators could not yet say the study was a success. Three other recently approved drugs for castration-resistant prostate cancer-Johnson & Johnson's Zytiga, Medivation's Xtandi, and Bayer's Xofigo-have deemed successful based on interim data. Shares of Exelixis ended the week down 46.3 percent.

 

 
BIGGEST MARKET MOVERS FOR THE WEEK ENDING MARCH 28, 2014

 

  TICKER

 

  COMPANY

  CLOSING
  PRICE
  3/214/2014
  CLOSING 
  PRICE 
  3/28/2014
  
  PRICE   
CHANGE
  
 PERCENT CHANGE
  ADVANCERS
HSKA
Heska Corporation
9.00
10.87
1.87
20.8%
AXDX
Accelerated Diagnostics
17.38
20.02
2.64
15.2%
KERX
Keryx Biopharmaceutical
14.84
16.61
1.77
11.9%
TSX:ECO
EcoSynthetix
2.18
2.43
0.25
11.6%
ALIM
Alimera Sciences
6.60
7.20
0.60
9.1%
  DECLINERS
EXEL
Exelixis
6.29
3.38
-2.91
-46.3%
ASTM
Aastrom Biosciences
6.49
4.06
-2.43
-37.4%
KPTI
Karyopharm Therapeutics
42.07
30.96
-11.11
-26.4%
RLYP
Relypsa
40.09
30.01
-10.08
-25.1%
LPDX
LipoScience
4.04
3.03
-1.01
-25.0%
Includes life sciences stocks with closing price of $1 or more on March 21, 2014
 

Axionics Raises $32.6M for Implantable Neuromodulation Technology

       

Startup receives bulk of funding from investors outside the United States.  

Axonics Modulation Technologies, launched in October 2013 by former senior management of Vessix Vascular, has raised $32.6 million in funding to develop a novel implantable neuromodulation technology to treat a number of clinical indications, including chronic pain and overactive bladder.

Read More Here


  BURRILL INDICES
12/31/13
3/21/2014
3/28/2014
Week Change
Year Change
Burrill Select
952.86
1054.10 996.58 -5.5% 4.6%
Burrill Large-Cap 1165.34 1281.79 1212.67 -5.4%
4.1%
Burrill Mid-Cap 537.96 565.49 519.20
-8.2%
-3.5%
Burrill Small-Cap 143.25 282.33 238.28 -15.6%
66.3%
Burrill Diagnostics 215.62 234.95 229.60 -2.3%
6.5%
Burrill Personalized Medicine 150.29 176.16 168.10 -4.6%
11.9%
Burrill Biogreentech 186.93 180.80 182.56 1.0%
-2.3%
NASDAQ 4176.59 4276.79 4155.76 -2.8%
0.5%
DJIA 16576.66 16302.77 16323.06 0.1%
-1.5%
S&P 500 1848.36 1866.52 1857.62 -0.5%
0.5%
Amex Biotech 2330.43 2795.99 2506.56 -10.4% 7.6%
Amex Pharmaceutical 468.07 498.08 495.32
-0.6% 5.8%
NASDAQ Biotechnology Index 2369.53 2577.21 2396.36 -7.0%
1.1%
The annual rebalance of the Burrill Indices took place on October 1, 2013.


Baxter to Split into Two Companies     
One will focus on drugs, the other on medical technology. 

Baxter International says it plans to split into two separate companies in order to maximize its long term growth prospects. One company will be focused on biopharmaceuticals and the other on medical products. The move follows similar recent moves by Abbott Labs, which spun out its biopharma unit into AbbVie, and Pfizer, which spun out its animal health unit Zoetis in an IPO.

Read More Here  

Global Telehealth Initiative Launched       
Mission is to deliver worldwide access to healthcare. 

A group of telehealth industry veterans have launched a new initiative with a mission to deliver access to healthcare worldwide. The TeleHealth International Partnership, or TIP is led by Jay Saunders, considered the father of telemedicine and Bernard Harris, an astronaut physician, both of whom are affiliated with the American Telemedicine Association. The initiative was orchestrated by Paula Guy, CEO of Global Partnership for TeleHealth.          

Read More Here 


New Procedure Converts Stem Cells into Muscle Cells    

Method advances use of stem cells in regenerative medicine.   

A research group at the University of Wisconsin-Madison has discovered a new way to make large concentrations of skeletal muscle cells and muscle progenitors from human pluripotent stem cells. The new procedure that converts stem cells into muscle cells is another step toward moving the use of stem cells into the clinic.   

Read More Here  

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