The Burrill Weekly Brief | April 07, 2014
BY THE NUMBERS
MannKind gets FDA advisory panel nod, shares up 42.2 percent
Though stocks opened higher on good March jobs data, investors continued to sell off momentum stocks, mostly high-growth companies in the biotech and tech sectors. The Burrill Biotech Select Index continued its month long slide, dropping another 2.3 percent for the week. For the week, the Nasdaq Composite Index fell 0.7 percent, while the S&P 500 (up 0.4 percent) and the Dow Jones Industrial Average (up 0.6 percent) ended the week fairly flat.
MannKind was the week's biggest mover with shares up 42.2 percent for the week. A U.S. Food and Drug Administration voted overwhelmingly to recommend approval of the biotech's inhaled insulin for the treatment of patients, both with type 1 and type 2 diabetes. This was MannKind's third attempt to win regulatory approval. Though the FDA does not have to follow advisory committee recommendations, it often does. The FDA has set April 15 as the date when it will make its decision.
Halozyme Therapeutics was the week's biggest loser. Shares ended the week down 30.4 percent after the company reported it was temporarily stopping enrollment of patients and dosing of its prostate cancer drug in a mid-stage trial, after an independent safety committee recommendation.
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BIGGEST MARKET MOVERS FOR THE WEEK ENDING MARCH 28, 2014
|
TICKER
|
COMPANY
|
CLOSING
3/28/2014
|
CLOSING
PRICE
4/4/2014
|
PRICE
CHANGE
|
PERCENT CHANGE
|
ADVANCERS
|
MNKD
|
MannKind
|
4.83
|
6.87
|
2.04
|
42.2%
|
ISR
|
IsoRay
|
2.31
|
3.03
|
0.72
|
31.2% |
SKYE.Y
|
SkyePharma
|
3.24
|
4.07
|
0.83
|
25.6%
|
MYGN
|
Myriad Genetics
|
32.87
|
40.99
|
8.12
|
24.7% |
JASDAQ:4579
|
RaQualia Pharma
|
4.62
|
5.58
|
0.96
|
20.9% |
DECLINERS
|
HALO
|
Halozyme Therapeutics
|
12.11
|
8.43
|
-3.68 |
-30.4%
|
DRNA
|
Dicerna Pharmaceuticals
|
29.05
|
21.41
|
-7.64
|
-26.3%
|
CRMD
|
CorMedix
|
2.66
|
2.05
|
-0.61 |
-26.4%
|
FATE
|
Fate Therapeutics
|
11.26
|
8.70
|
-2.56 |
-22.7%
|
GALT
|
Galectin Therapeutics
|
15.72
|
12.21
|
-3.51 |
-22.3%
|
Includes life sciences stocks with closing price of $1 or more on March 28, 2014
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Intarcia Therapeutics has raised another $200 million in private financing, which together with the $210 million round of equity and debt financing in November of 2012, puts the company in a strong position to complete a late-stage clinical trial and prepare to launch its once yearly diabetes treatment, and to build its pipeline.
Read More Here
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BURRILL INDICES
|
12/31/13
|
3/28/2014
|
4/4/2014
|
Week Change
|
Year Change
|
Burrill Select |
952.86
|
996.58 |
973.24 |
-2.3% |
2.1% |
Burrill Large-Cap |
1165.34 |
1212.67 |
1186.13 |
-2.2%
|
1.8% |
Burrill Mid-Cap |
537.96 |
519.20 |
511.04
|
-1.6%
|
-5.0% |
Burrill Small-Cap |
143.25 |
238.28 |
222.10 |
-6.8%
|
55.0% |
Burrill Diagnostics |
215.62 |
229.60 |
233.03 |
1.5%
|
8.1%
|
Burrill Personalized Medicine |
150.29 |
168.10 |
168.14 |
0.0%
|
11.9% |
Burrill Biogreentech |
186.93 |
182.56 |
183.48 |
0.5%
|
-1.8% |
NASDAQ |
4176.59 |
4155.76 |
4127.73 |
-0.7%
|
-1.2% |
DJIA |
16576.66 |
16323.06 |
16412.71 |
0.5%
|
-1.0% |
S&P 500 |
1848.36 |
1857.62 |
1865.09 |
0.4%
|
0.9% |
Amex Biotech |
2330.43 |
2506.56 |
2499.57 |
-0.3% |
7.3%
|
Amex Pharmaceutical |
468.07 |
495.32 |
495.22
|
0.0% |
5.8%
|
NASDAQ Biotechnology Index |
2369.53 |
2396.36 |
2356.60 |
-1.7%
|
-0.5%
|
The annual rebalance of the Burrill Indices took place on October 1, 2013.
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Forma Therapeutics has entered into a second strategic collaboration with Celgene focused on unmet needs in genetically driven therapeutic areas. The deal comes with $225 million in upfront cash and an option to be acquired by Celgene at a specified point during the partnership.
Read More Here
AbbVie has dropped its challenge to the European Union court to block the European Medicines Agency from releasing clinical trial data from the company, reports Bloomberg. AbbVie's decision comes amid European regulators efforts to push for more clinical trial transparency.
Read More Here
Patients with severe ischemic heart disease and heart failure benefited from a new treatment in which stem cells found in bone marrow are injected directly into the heart muscle, according to Danish researchers.
Read More Here
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